产品货号：
Z17786
中文名称：
GSTM1抗体
英文名称：
Anti-GSTM1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GSTM1 Antibody |
| 指标别名 | glutathione S transferase mu 1;GST class mu 1;GST HB subunit 4;GST1;GSTM1;GSTM1 1;GSTM1a 1a;GSTM1b 1b;GTH4;GTM1;H B;MU;MU 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IF,ICC,FCM |
| 基因名称 | GSTM1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of human GSTM1 (EEEKIRVDILENQTMDNHMQLGMICYNPEFEKLK). |
| 实际分子量 | 26KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Glutathione S-transferase Mu 1 (gene name GSTM1) is a human glutathione S-transferase.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families.At present,eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified:alpha,kappa,mu,omega,pi,sigma,theta and zeta.This gene encodes a glutathione S-transferase that belongs to the mu class.The mu class of enzymes functions in the detoxification of electrophilic compounds,including carcinogens,therapeutic drugs,environmental toxins and products of oxidative stress,by conjugation with glutathione.The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic.These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.Null mutations of this class mu gene have been linked with an increase in a number of cancers,likely due to an increased susceptibility to environmental toxins and carcinogens.Multiple protein isoforms are encoded by transcript variants of this gene. |
| Uniprot ID | P09488 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Flow cytometry (FCM) 1～3μg/1×106 cells Immunohistochemistry in frozen section 1:50～400 Immunocytochemistry in fixed cells 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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